UFP500 is a proprietary particle technology platform that transforms how bioactive compounds behave — unlocking bioavailability, formulation flexibility, and ingredient performance that conventional processing cannot reach. The particle size achieved in any application is defined by the science of that application. The goal is always performance.
UFP500 is a proprietary technology platform developed and operated by BioFund — selectively opened to mission-aligned commercial partners where the science and application are a genuine fit.
UFP500 achieves ultra-fine particle reduction without heat, pressure, solvents, or additives. Enzymatic activity, polyphenol integrity, and volatile compounds are preserved through the full processing cycle. The output is clean-label by design — nothing added, nothing compromised.
Processed material exits as a dry, stable, ultra-fine powder — ready for direct incorporation into capsules, functional foods, veterinary formulations, and cosmetic carriers without further milling or re-processing.
Reducing particle size to the 1–5 μm range increases surface area by 50–100× relative to conventionally processed material. That surface area change is what drives dissolution rate, absorption kinetics, enzymatic contact, and dispersion behaviour. The particle size is a proxy. The performance is the point.
UFP500 is the processing backbone of BioFund's own therapeutic and nutritional research pipeline. Every ingredient category we have processed has been evaluated against measurable bioactivity and formulation criteria — not marketing logic.
Ultra-fine particle processing unlocks performance that conventional processing cannot reach — across food, health, beauty, and science. Each application area represents an active development direction, not a theoretical capability.
Ultra-fine particle processing transforms how bioactive ingredients behave in food and drink matrices. Powders that genuinely dissolve, disperse, and integrate — delivering the nutrition and function on the label, not just the ingredient name. Functional beverages, enhanced food formats, and precision nutrition applications where bioactives survive processing and reach the consumer intact.
Ultra-fine grain and botanical powders change dough rheology, crust behaviour, crumb structure, fermentation dynamics, and nutritional density simultaneously. This is not an additive approach — it is a fundamental change in how the material behaves in the matrix. Active development underway with craft bakery partners exploring what ultra-fine malt, grain, and botanical powders make possible.
Ultra-fine particle processing unlocks entirely new culinary possibilities. Natural ingredients become lighter, smoother, more aromatic, and more expressive — allowing chefs, artisan producers, and premium food brands to create experiences that were previously impossible. Colour that integrates rather than settles. Flavour that opens rather than crowds. RAFFINÉ is the active proof of concept — a premium botanical culinary line built on UFP500 processing from the outset.
Ultra-fine particle processing of botanicals for functional amaro, vermouth, bitters, and craft spirits — where particle scale governs extraction efficiency and sensory precision. Colour, aroma, and botanical character that integrates rather than intrudes. The Amaro Mare concept, built on coastal botanical matrices, is the active R&D direction — a genuine intersection of food science, flavour chemistry, and bioactive platform thinking.
At sub-10 micron particle scale, natural actives interact with skin at a fundamentally different level. Pigments liberated without grittiness. Botanical actives that penetrate rather than sit on the surface. Natural colour for clean-label cosmetics that performs like synthetic. UFP500 processing opens a genuine pathway for natural ingredient performance in premium skincare, colour cosmetics, and cosmeceutical formulations.
UFP500-processed botanical therapeutics are the formulation core of BioFund's companion animal oncology pipeline — enabling bioactive delivery at dose levels achievable in palatability-driven daily formats. The OneHealth methodology validates botanical concepts in companion animals first. Livestock and aquaculture feed applications extend the same platform logic: botanical alternatives to antibiotics where dose efficiency is the entire commercial argument.
Botanical materials processed to particle scales where absorption kinetics, mucosal uptake, and enzymatic activity change in ways pharma-grade formulation demands. No adjuvants, no solvents, no synthetic enhancement — the full botanical matrix, made genuinely available. For pharmaceutical and nutraceutical partners working where botanical science meets clinical evidence.
Whole botanical matrices processed to ultra-fine particle scale — no isolates, no solvents, no synthetic enhancement — where the body can access what the plant actually contains. Capsules, sachets, stick packs, and functional bars built on ingredients that genuinely perform at the dose stated. The SENTINEL firefighter nutrition programme is the active proof of concept.
Industrial food, aquaculture, and agriculture generate enormous volumes of side streams that conventional technology cannot valorize beyond low-grade disposal. UFP500 changes that equation completely. The same platform that transforms premium botanicals applies equally to crustacean shell biomass, fruit and vegetable pomace, grain fractions, and seed press cakes — converting what industry treats as a disposal problem into premium functional ingredients. The physics does not distinguish between inputs by origin. It asks only what the material contains, and what it can become.
Crustacean shell biomass, microalgae, and coastal botanical matrices. Ultra-fine processing unlocks chitin fractions, marine polyphenols, carotenoids, and enzyme systems that standard processing cannot access.
Processing industry pomace retains significant residual bioactive value — anthocyanins, ellagitannins, and carotenoid fractions that respond strongly to ultra-fine particle processing with cold-process preservation.
Malt fractions, whole grain side streams, and seed press cakes. Ultra-fine particle processing changes how these materials behave in dough matrices, fermentation systems, and functional food formats.
UFP500 is a processing platform. What makes it different from conventional milling is not only the particle scale it achieves — it is how it gets there, and what that means for everything that follows.
The clean label, the natural integrity, and the circular potential of UFP500-processed ingredients are not positioned values. They are physical consequences of how the platform operates — dry, cold-process, without solvents, carriers, or synthetic addition of any kind. The compound that enters UFP500 is the compound that leaves it. Nothing is added. Nothing is changed. It is simply made smaller, and in being made smaller, it becomes more of what it already was.
UFP500 processes without carriers, solvents, binders, or synthetic enhancement. Nothing is added. The clean label declaration is not a positioning choice — it is what dry, cold-process mechanical particle reduction produces by definition. Formulators using UFP500-processed material declare the botanical itself. That is all there is to declare.
Achieving ultra-fine particle scale without destroying heat-sensitive structures requires a cold process. UFP500 is built around exactly that — preserving enzymatic activity, polyphenol integrity, and volatile fraction that make natural ingredients worth processing in the first place. The compound arrives in the formulation as it existed in the plant. Smaller. More accessible. Unchanged in everything that matters.
The same physics that transforms premium botanicals into high-performance ingredients applies equally to industrial side streams — crustacean shell biomass, fruit pomace, grain fractions, seed press cakes — that conventional technology discards. UFP500 converts what industry treats as low-value disposal into premium functional ingredients. The platform asks only one question of any natural material: what does it contain, and what can it become?
We select partners based on mission alignment, genuine scientific depth, and the potential for long-term collaboration. The process reflects that.
Tell us about your ingredient, your application, and what you're trying to achieve. We'll be direct about whether UFP500 is genuinely relevant for your use case.
If the initial fit is clear, we conduct a rapid feasibility assessment — processing a small sample batch and evaluating particle output, stability, and bioactivity against your target specifications.
A structured pilot programme with defined endpoints, documented protocols, and measurable outcomes — the basis for a commercial partnership agreement.
Successful pilots move to partnership — with co-development rights, IP protections, and access to BioFund's research network built into the arrangement from the outset.
BioFund brings the UFP500 platform to partnerships as an invested resource — not a fee-for-service. We expect future cost-sharing and co-funding as collaborations mature, structured fairly around shared outcomes.
For companies seeking to integrate UFP500-processed ingredients into commercial products. We work with food, supplement, veterinary, and pharmaceutical manufacturers where the fit is genuine.
For academic and institutional research partners exploring bioavailability, particle science, or novel ingredient categories. BioFund brings the platform; partners bring the scientific discipline and publication mandate.
UFP500° is the distinction mark carried by products built on ultra-fine particle processed ingredients — a signal that the processing standard behind the product changes how the ingredients perform. The first two mark holders are our own: proof that we build what we believe in before we ask others to.
The art of the invisible. RAFFINÉ transforms single ingredients to ultra-fine particle scale — unlocking flavour, colour, and texture that conventional processing cannot reach. Structured around Seven Worlds of transformation: Forest, Garden, Orchard, Ocean, Seed, Field, and Alchemy. The first UFP500° mark holder in the culinary and premium food category.
raffineculinary.com →Ultra-fine superior functional botanicals. PURE demonstrates what whole-plant botanical formulation looks like when built on the UFP500 processing standard — complete botanical matrix, no isolates, no extraction, no compromise. Structured as a biological hierarchy across eight functional categories. The first UFP500° mark holder in the precision wellness category.
pure.ufp500.com →The UFP500° distinction mark is available to commercial partners who build products on UFP500-processed ingredients and meet the processing standard. If you are developing a product where the quality of what is inside should be visible on the outside — the conversation starts here.
Bring your ingredient, your concept, or your customer brief — and we will figure out together whether there is a pilot worth starting. Co-funded. Real products. Shared outcomes.
Particle physics, bioavailability mechanisms, processing protocols, and validation data — for scientists and researchers who want to understand how UFP500 works, not just what it does.
Tell us about your application and we'll respond with a direct assessment of fit. No sales process — just an honest conversation about whether UFP500 can genuinely help.